SkinCeuticals P-TIOX Anti-Wrinkle Serum: The Needle-Free Alternative to Neurotoxin Injections

SkinCeuticals P-TIOX Anti-Wrinkle Serum is a breakthrough peptide serum inspired by the mechanism of anti-wrinkle neurotoxin injections — delivering clinically proven wrinkle correction without needles, downtime, or a physician visit. As one of SkinCeuticals' top best-sellers with 8,554 purchases in the last month alone, this skinceuticals p-tiox serum has rapidly become the go-to solution for anyone seeking advanced anti-aging correction for expression lines and glass skin radiance.

P-TIOX features a patent-pending technology combining an advanced peptide complex (Acetyl Hexapeptide + Dipeptide Diaminobutyroyl Benzylamide Diacetate) with three potent synergistic actives — 5% Polyhydroxy Acid (PHA), 5% Niacinamide, and 1% Laminaria Extract. In clinical studies, this unique combination showed powerful synergy superior to peptide-based formulas alone, visibly reducing 9 types of expression lines — including areas that neurotoxin injections typically do not treat — while revealing dramatically smoother, more radiant glass skin in as little as 1 week.

Key Benefits

• Clinically reduces the appearance of 9 types of expression lines in 12 weeks
• Reveals glass skin radiance and visibly improves skin smoothness in just 1 week
• 20% reduction in global fine lines in clinical studies
• 16% improvement in skin smoothness after 12 weeks
• 10% improvement in overall skin radiance
• Physician-tested to complement neurotoxin injections — reduces 5 additional wrinkle types in 1 month post-injection
• Effective as a standalone needle-free wrinkle correction serum — no injectables required
• Intensely moisturizes skin for up to 24 hours after application
• Suitable for all skin types and tones, including sensitive skin
• Fragrance-free, silicone-free, paraben-free, dye-free
• TSA-approved travel size available
• 8,554 purchases in the last month — SkinCeuticals Best Seller

Key Ingredients

• Advanced Peptide Complex (Acetyl Hexapeptide-8 + Dipeptide Diaminobutyroyl Benzylamide Diacetate): A dual-peptide complex inspired by neurotoxin injection technology — works to relax facial muscle contractions that cause expression lines, reducing the visible appearance of contraction-related wrinkles across 9 areas of the face
• 5% Polyhydroxy Acid (PHA): A gentle, next-generation exfoliating acid that promotes cell turnover, refines skin texture, minimizes pores, and enhances overall radiance — without the irritation associated with AHAs or BHAs
• 5% Niacinamide (Vitamin B3): Strengthens the skin's moisture barrier, reduces the appearance of discoloration and blotchiness, minimizes pore appearance, and supports even skin tone — amplifying the radiance-boosting effects of the peptide complex
• 1% Laminaria Extract (Brown Seaweed): A natural marine-derived ingredient that deeply hydrates, soothes skin, and provides a calming, anti-inflammatory effect — contributing to the formula's exceptional tolerance profile even on sensitive skin

• Use twice daily — morning and evening
• Apply 4–6 drops of P-TIOX anti-wrinkle serum to the palm of the hand
• Dab onto the forehead, cheeks, and chin
• Blend gently into the skin using upward, outward motions
• Morning routine: Apply after a SkinCeuticals vitamin C antioxidant serum (such as C E Ferulic) and before a SkinCeuticals sunscreen
• Evening routine: Apply after cleansing and toning, before moisturizer
• Can be used with retinol — apply P-TIOX first, then retinol at night
• Can be used alongside neurotoxin injections — physician-tested to enhance injectable results in non-injected areas
• For best results, use consistently twice daily for a minimum of 12 weeks

Key Active Ingredients: Acetyl Hexapeptide-8 (Hexapeptide), Dipeptide Diaminobutyroyl Benzylamide Diacetate (Dipeptide), Polyhydroxy Acid (PHA) 5%, Niacinamide 5%, Laminaria Digitata Extract 1%.

Additional Ingredients: Aqua/Water/Eau, Butylene Glycol, Glycerin, Sodium Hyaluronate, Pentylene Glycol, Hydroxyethylcellulose, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Citric Acid.

Please refer to product packaging for the most accurate and up-to-date full ingredient list. P-TIOX is fragrance-free, silicone-free, paraben-free, and dye-free.

• BrandSkinCeuticals
• Product TypePeptide Anti-Wrinkle Serum
• Volume30ml / 1 fl. oz.
• Key TechnologyPatent-Pending Peptide Complex + Synergistic Actives
• Key IngredientsHexapeptide + Dipeptide Complex, 5% PHA, 5% Niacinamide, 1% Laminaria Extract
• FragranceFragrance-Free
• SiliconeSilicone-Free
• ParabenParaben-Free
• DyeDye-Free
• Usage TimeMorning & Evening (Twice Daily)
• Suitable ForAll Skin Types Including Sensitive
• Injectable CompatiblePhysician-Tested to Complement Neurotoxin Injections
• TSA ApprovedYes
• Clinical Results20% reduction in fine lines, 16% improved smoothness, 10% improved radiance (12 weeks)

Skin Type: Normal SkinDry SkinCombination SkinOily SkinSensitive SkinAging SkinAll Skin Types

Skin Concern: Fine Lines and WrinklesExpression LinesForehead WrinklesCrow's FeetNasolabial FoldsMarionette LinesGlabellar WrinklesUneven Skin TextureDullnessLarge PoresLoss of RadianceAging Skin